Depression

Definium's LSD-based drug lowers anxiety in second successful late-stage study

A single 100-microgram dose of DT120, a fast-dissolving tablet of lysergide, the chemical name for the psychedelic drug LSD, reduced scores on an anxiety scale by 9.8 points after 12 weeks.

Sad, child and crying on floor in home with mental health, abuse or anxiety from trauma.
Lindsay Clancy listens in the coutroom during her murder trial at Plymouth Superior Court in Plymouth, Massachusetts, U.S., August 13, 2026.

Defense in Lindsay Clancy case claims psychosis behind her killing her children

The path back to ourselves.

Healing overloaded minds: How Israel's prolonged war is affecting memory, concentration

OR AVINOAM (left) and Riki Reif Sinai in ‘Cuz You’re Ugly.’

In 'Cuz You're Ugly,' Israeli director Sharon Angelhart tells the story she never saw on screen


Mental health crisis spinning out of control

A global study across 204 countries found that nearly 1.2 billion people lived with a mental disorder in 2023: a surge of 95.5% since 1990, with anxiety and depression leading the increase.

Mental health crisis spinning out of control

Iran’s digital divide: Iranians without internet suffering from isolation, depression - study

Nearly every interviewee spoken to by Filterbaan mentioned wanting to leave Iran, in part due to the internet ban as part of a wider crackdown on personal freedom.

An online teacher, Nazafarin, works on her laptop at home, after a nationwide internet shutdown since January 8, 2026, following Iran's protests, in Tehran, Iran, January 24, 2026.

Trump’s mental health order pushes psychedelic research into the mainstream - opinion

Trump’s order is not perfect. and requires oversight, transparency, responsibility, and caution, but it does one thing right: it moves the system forward.

Depression is not a temporary bad mood or a short period of sadness, but a significant mood disorder that may affect daily routine, everyday functioning, and relationships

Study finds – women experience depression at twice the rate of men

Depression in women may appear in different intensities and forms, but behind the symptoms lies a complex combination of hormonal, psychological, and social factors.

Depression is not a temporary bad mood or a short period of sadness, but a significant mood disorder that may affect daily routine, everyday functioning, and relationships

Research ties GLP-1 injections to fewer setbacks in anxiety and depression

The study also reported a 42% lower risk of psychiatric hospitalizations and work absences during periods when patients were taking semaglutide compared with periods when they were not.

A combination image shows an injection pen of Zepbound, Eli Lilly's weight loss drug, and boxes of Wegovy, made by Novo Nordisk.

Researchers reveal the surprising reason for the rise in loneliness in the world

In the shadow of the war and the prolonged stay at home, experts warn that chronic loneliness has become a global health crisis.

The surprising reason for the rise in loneliness in the world

Pharmaceutical companies are shaking: Israeli pharma company with breakthrough development

PsyRx develops a treatment to speed antidepressant effects using controlled ibogaine. Prof. Grutto: "We need solutions that grasp the medical urgency."

Beer, Depression, Alcoholism.

When tension with Iran feels like a weather forecast, depression isn’t surprising

From an evolutionary perspective, the human brain was not designed to live under extreme stress for long periods of time – and when it does, it pays a price.

The cost is disconnection and emotional constriction

Sexual minority Israelis report higher depression, anxiety, suicide ideation, study finds

The study, conducted by researchers affiliated with the University of Haifa and Ben-Gurion University of the Negev, drew on a cross-sectional online survey of 465 adults in Israel.

A depressed woman

Israel must confront the growing economic toll of depression - opinion

Depression is costing Israel is costing the country between an estimated NIS 12 billion and NIS 16 billion per year.

The antidepressant drug Prozac, also known as fluoxetine, is seen on a table in Leicester, central England February 26, 2008 in this posed photograph.